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Which type of dependence can be associated with Schedule III drugs?

  1. Only severe physical dependence

  2. Moderate or low physical dependence and high psychological dependence

  3. No dependence whatsoever

  4. Severe psychological dependence only

The correct answer is: Moderate or low physical dependence and high psychological dependence

Schedule III drugs are classified as substances that have a potential for abuse but are considered to have medical uses. The correct option indicates that these drugs can lead to moderate or low physical dependence along with high psychological dependence. This aligns with the characteristics of Schedule III substances, which often encompass anabolic steroids, certain depressants, and some stimulants. These drugs are associated with a lower risk of severe physical dependence compared to Schedule I and II substances; however, they can still lead to significant psychological dependence. The psychological aspect means that individuals may develop a strong desire or compulsion to use the drug to achieve its effects, despite potential adverse consequences. Thus, they can be abused with a potential for addiction even while the physiological aspects of dependence are less pronounced than with higher-schedule drugs. Options that suggest only severe physical dependence, no dependence at all, or only severe psychological dependence do not accurately reflect the established understanding of the dependence potential associated with Schedule III substances.